What does the acronym "CADHERIN" refer to in cellular biology?

• A. Calcium-Dependent Adhering of tissues
• B. Calcium-Dependent Adhering of cells
• C. Calcium-Induced Dissolution of cells
• D. Calcium-Dependent Adhesion of nerve cells

Answer: (B)

The term "CADHERIN" refers to a type of protein that plays a critical role in cell adhesion, specifically the adhesion of cells to each other. These proteins are dependent on calcium ions to function effectively, which is intrinsic to their structural integrity and capability to mediate the adhesion process. The primary role of cadherins is to form strong cell-to-cell connections, which are essential for maintaining tissue structure and integrity in multicellular organisms.

The correct interpretation emphasizes that cadherins facilitate the adherence of cells to one another, ensuring proper cellular organization and signaling within tissues. This process is vital in various biological contexts, including embryonic development, immune response, and the maintenance of tissue architecture. The designation of cadherins as "calcium-dependent" highlights the necessity of calcium ions for their binding activities, which reinforce the significance of the name in cellular biology.